Anywhere in the world

Wako is there to support your endotoxin testing needs

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Pyrostar Endotoxin specific reagents

Check out the new PYROSTAR™ ES-F line for the detection of bacterial endotoxin

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Endotoxin-free accessories

Check out our catalog of LAL Accessories

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Toxinometer® Measurement System

The Toxinometer® ET-6000 is our new computer-operated kinetic incubating tube reader

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About Wako's LAL Division

Long recognized as a world-renowned supplier of high purity chemicals and reagents, Wako Chemicals USA, Inc continues to maintain a proud history of product quality and customer service through the establishment of our LAL Division, and the introduction of our new PYROSTAR™ ES-F line for the detection of bacterial endotoxin.

As an FDA licensed facility, Wako Chemicals USA, Inc. – LAL Division is committed to ensuring that our production site and LAL reagents comply with all the rules, regulations, and quality standards set forth by FDA for current Good Manufacturing Practices (cGMP’s)

Horseshoe Conservation

U.S. Fish and Wildlife ServiceWako Chemicals USA, Inc. is very much concerned with maintaining the viability of the horseshoe crab population. We are dedicated to following practices that ensure the careful handling and good quality of crabs used for LAL manufacture that both minimize injury and protect this invaluable species. After bleeding, the crabs are returned the next day by our fisherman to the same waters where they were collected. To assist in the collection of data for crab conservation studies, Wako USA participates in a horseshoe crab tagging and monitoring program coordinated by the U.S. Fish and Wildlife Service. For more information, visit Wako´s Commitment For Horseshoe Crab Conservation

 

 

 

 

About Our Products

LAL Reagent Kit

LAL Reagents

Welcome to our LAL Reagents section. On this page, you will be able to browse through our gallery of Limulus Amebocyte Lysate products for the detection of Gram-negative bacterial endotoxins. Choose from our different detection methods and request quotes now!

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LAL Accessories for Bacterial Endotoxin Test

LAL Accessories

To complement our limulus amebocyte lysate (LAL) reagent product line, our trademark PYROSTAR offers accessories, kits and solutions for use in the different endotoxin detection assays. View Gel Clot Reaction Tubes, Lysate Reagent Water, Toxinometer® ET-6000 Series and more.

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LAL Distributors

LAL Distributors

Our FDA-licensed LAL reagents and related accessories are available from our network of distributors around the world. Search for your location and find contact details of our resellers in your country. Are you interested in becoming a distributor of our LAL reagents? Contact Us Now.

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Featured Products

 Kit of 4 PYROSTAR™ ES-F (2 ML) with CSE

Kit of 4 PYROSTAR™ ES-F (2 ML) with CSE

PYROSTAR™ ES-F Multi Test Vial (2.0 mL and 5.2 mL) with Control Standard Endotoxin (CSE) Intended Use: Limulus...

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Toximaster QC7 software package

Toximaster QC7 software package

Toximaster QC7 software package – designed to use with the Biotek ELx808IU microplate reader

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Kit of 100 PYROSTAR™ ES-F (5.2 ML) without CSE

Kit of 100 PYROSTAR™ ES-F (5.2 ML) without CSE

PYROSTAR™ ES-F Multi Test Vial (2.0 mL and 5.2 mL) Intended Use: Limulus amebocyte lysate (LAL) is...

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Limulus Color KY Series

Limulus Color KY Series

The Limulus Color KY Series includes both a multi-test kit and a single-test kit, each designed...

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BioClean® Series

BioClean® Series

Wako's premiere collection of endotoxin-free pipette tips, test tubes and caps designed for worry free endotoxin testing...

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Gel Clot Reaction Tubes

Gel Clot Reaction Tubes

Our Gel Clot Reaction Tubes are made of high quality Borosilicate glass and certified free of...

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Toxinometer ET-6000 Series

Toxinometer ET-6000 Series

The Toxinometer® ET-6000 is our new computer-operated kinetic incubating tube reader, which is exceptionally user-friendly and easily...

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Pyrostar ES-F Single Test Vial

Pyrostar ES-F Single Test Vial

*PYROSTAR™ ES-F* Single Test Vial Intended Use: Limulus amebocyte lysate (LAL) is intended for the detection of gram-negative...

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Blog

Potential applications of the Horseshoe Crab in the development of health products
Potential applications of the Horseshoe Crab in the development of health products

The Horseshoe Crab from the Atlantic, commonly known as _Limulus polyphemus, _has existed for more than 200 million years. It has been classified under the category Arthropods since the 19th century, and not under Crustaceans as it was first thought. This close relative of Arachnids has historically been harvested for

The Role of LPS in the Progression of Diabetic Nephropathy
The Role of LPS in the Progression of Diabetic Nephropathy

Lipopolysaccharides (LPS) or bacterial endotoxins are associated with a large range of pathologies. Some of these are tumor necrosis, neuroinflammation, bacteriobilia, respiratory diseases, coronary artery diseases, neonatal necrotizing enterocolitis, neurodegenerative diseases, cystic fibrosis, autoimmune diseases and even male infertility, as we mentioned before. In this article, we will talk about

Male Infertility Caused by Bacterial Lipopolysaccharides
Male Infertility Caused by Bacterial Lipopolysaccharides

The spermatozoon is the male gamete whose function is to lead the DNA towards the egg (female gamete) and form a zygote that will later turn into the embryo and the fetus. Therefore, the sperm count is considered to be of great importance for public health primarily because it is

Association of Bacterial Lipopolysaccharides in the Pathology of Alzheimer’s Disease
Association of Bacterial Lipopolysaccharides in the Pathology of Alzheimer’s Disease

Gram-negative bacteria are reported as the predominant microorganisms in the normal human brain. In previous articles, we have discussed the mechanisms that lipopolysaccharide endotoxins (LPS) possess to cause neuroinflammation and its results. However, research has gone a little further, associating these molecules with the clinical appearance of neurodegenerative diseases like