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Kits for the LAL test via the Gel-Clot Method

Aug 30, 2018
lal kits used in the gel clot method

The amebocyte lysate extracted from the horseshoe crab is capable of detecting very little quantities of bacterial endotoxins, which makes it possible to develop kits with a very low limit of detection. The analytical signal used in the LAL test with the Gel-Clot method is gel formation.The qualitative analysis with...

By: Default Admin
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The use of the Gel-Clot Method in the LAL test

Aug 24, 2018
the use of the gel clot method in the lal test

The LAL test (Limulus Amebocyte Lysate) is used to determine the presence of bacterial endotoxins in biological samples or samples of other types. This analysis can be performed using the Gel-Clot method, or gelation for detection as a gel is formed if the test is positive.The bacteria could lead to...

By: Lisa Komski Tags: LAL test
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Kits for the LAL test with the Turbidimetric Method

May 21, 2018
kits lal test turbidimetric method

The brand PYROSTAR has different kits to conduct the LAL test, that is, for the detection of bacterial endotoxins. Some of these kits are designed to be used with the turbidimetric methods of analysis. The analytical sign that can be measured and quantified through these kits is the turbidity formed...

By: Lisa Komski In: Kit LAL Tags: Turbidimetric Method, LAL test
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The use of the Turbidimetric Method in the LAL test

Apr 20, 2018
turbidimetric method in the lal test

The turbidimetric method is one of the methods used for the detection of the end point when endotoxin analysis is performed using the Limulus Amebocyte Lysate (LAL) test. By applying the turbidimetric method, we can conduct the LAL test in a semi-quantitative or quantitative manner.The LAL test measures the turbidity...

By: Lisa Komski In: Kit LAL
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Analytical Methods for the detection of bacterial endotoxins

Mar 15, 2018
methods for the detection of bacterial endotoxins

There are three analytical methods for the determination of bacterial endotoxins through the Limulus Amebocyte Lysate test, also known as the LAL test by its acronym. These methods are the Gel-Clot method, the turbidimetric method and the colorimetric method, which can be carried out in a qualitative or quantitative manner.Gel-Clot...

By: Lisa Komski In: Kit LAL
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The importance of having the right accessories to carry out the LAL test

Feb 16, 2018
accessories suitable for carrying out the lal test

The LAL test (Limulus Amebocyte Lysate) allows us to determine lipopolysachharides of bacterial origin. The lipopolysachharide molecules found in the outer cell wall of Gram-negative bacteria, also known as bacterial endotoxins, are released when bacterial lysis takes place. These substances have a high level of toxicity and are very stable,...

By: Lisa Komski In: Kit LAL
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Where and why is the LAL test performed?

Jan 23, 2018
where and why is the lal test performed

The LAL test (acronym for Limulus Amebocyte Lysate) is a test for the determination of bacterial endotoxins, which uses an Amebocyte Lysate of the Limulus crab. In this test, the reactions which occur in the Amebocyte Lysate as a result of a defence mechanism of the crab in the presence...

By: Lisa Komski
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Reagents and Accessories for the Limulus Amebocyte Lysate Test (LAL)

Jan 8, 2018
reagents and accessories for the limulus amebocyte lysate test

The Limulus Amebocyte Lysate Test (LAL) is a method for the detection and quantification of bacterial endotoxins that is widely used by the pharmaceutical and biotechnology industry. The biochemical principle of the test is based on the clotting reaction of the hemolymph of the Limulus polyphemus, commonly known as the...

By: Lisa Komski In: Kit LAL
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Potential applications of the Horseshoe Crab in the development of health products

Nov 9, 2017
the horseshoe crab and its importance for health

The Horseshoe Crab from the Atlantic, commonly known as Limulus polyphemus, has existed for more than 200 million years. It has been classified under the category Arthropods since the 19th century, and not under Crustaceans as it was first thought. This close relative of Arachnids has historically been harvested for...

By: Lisa Komski In: Kit LAL
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The Role of LPS in the Progression of Diabetic Nephropathy

Sep 26, 2017
lps in the progression of diabetic nephropathy

Lipopolysaccharides (LPS) or bacterial endotoxins are associated with a large range of pathologies. Some of these are tumor necrosis, neuroinflammation, bacteriobilia, respiratory diseases, coronary artery diseases, neonatal necrotizing enterocolitis, neurodegenerative diseases, cystic fibrosis, autoimmune diseases and even male infertility, as we mentioned before.In this article, we will talk about another...

By: Lisa Komski In: Kit LAL
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