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Male Infertility Caused by Bacterial Lipopolysaccharides

Sep 1, 2017
male infertility caused by lps

The spermatozoon is the male gamete whose function is to lead the DNA towards the egg (female gamete) and form a zygote that will later turn into the embryo and the fetus. Therefore, the sperm count is considered to be of great importance for public health primarily because it is...


By: Lisa Komski
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Association of Bacterial Lipopolysaccharides in the Pathology of Alzheimer’s Disease

Jun 30, 2017
bacterial lipopolysaccharides in alzheimers disease

Gram-negative bacteria are reported as the predominant microorganisms in the normal human brain. In previous articles, we have discussed the mechanisms that lipopolysaccharide endotoxins (LPS) possess to cause neuroinflammation and its results. However, research has gone a little further, associating these molecules with the clinical appearance of neurodegenerative diseases like...


By: Lisa Komski In: Kit LAL
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Immunomodulation by Bacterial Lipopolysaccharides

May 31, 2017
immunomodulation by bacterial lipopolysaccharides

Lipopolysaccharides (LPS) or bacterial endotoxins are a molecule that is amply found in the outer membrane of gram-negative bacteria, except for species of the Sphingomonas genus, which have glucosphingolipids instead. Although at high concentrations LPS can induce fever, increased heart rate, septic shock and death, at relatively low concentrations some...


By: Lisa Komski In: Kit LAL
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Bile contamination or Bacteriobilia, a risk factor in post-operative complications

Apr 5, 2017
bile contamination caused by gram negative bacteria

Bacterial endotoxins, as we already discussed in previous reviews, constitute the lipid part of the lipopolysaccharide molecule, which forms the outer membrane of the gram-negative bacterial cell, and they are an important factor in the pathogenicity of the microorganism. They are responsible for potentially life-threatening diseases, such as cholera and...


By: Lisa Komski In: Kit LAL
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Gram-negative bacteria: opportunistic infections in patients with HIV/AIDS

Mar 24, 2017
infections in hiv patients caused by gram negative bacteria

Based on recent estimates conducted by scientists from Israel and Canada, there is a ratio of about 1,3:1 between bacterial cells and human cells, with an uncertainty of 25% and a variation of 53% relative to a standard male population of 70 kg. The vast majority of these commensal bacteria...

Neuroinflammation caused by bacterial endotoxins

Jan 25, 2017
neuroinflammation caused by bacterial endotoxins

Lipopolysaccharide endotoxins or bacterial endotoxins are lipopolysaccharide molecules constituting the outer membrane of Gram-negative bacteria and they are released into the environment when cell lysis occurs. These molecules have a high level of toxicity in other organisms and therefore, they are called endotoxins. The damages that are produced in mammals...


By: Lisa Komski In: Kit LAL
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Different environments where bacterial endotoxins can be found

Dec 22, 2016
environments where bacterial endotoxins can be found

Bacterial endotoxins originate from Gram-negative bacteria, which, after death, are released to the environment where they encounter lipopolysaccharides, which constitute their cell wall and which are highly toxic substances to other organisms . These endotoxins are considered to be the most frequently reported pyrogens. Bacterial endotoxins cause infections that can...

Treatment of sepsis caused by Gram-negative bacteria

Nov 17, 2016
treating sepsis caused by gram negative bacteria

The most common treatment for sepsis caused by bacteria, whether Gram-positive or Gram-negative, is the use of antibiotics. When sepsis is caused by Gram-negative bacteria, antibiotic therapies have the disadvantage of producing an increase in the bacterial endotoxin levels in the blood plasma of patients. The highest concentration of bacterial...


By: Lisa Komski In: Kit LAL
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The Use of Toxinometer ET-6000 in LAL test

Sep 22, 2016
toxinometer et 6000 in lal test

Toxinometer® ET-6000 is the new equipment developed by the company Wako for the reading of tubes in which the LAL (Limulus Amebocyte Lysate) test is performed for the quantification of bacterial endotoxins in a sample. Today the LAL test is considered to be the most effective method for the detection...


By: Lisa Komski In: Kit LAL
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Mechanisms of cellular stimulation by bacterial endotoxins

Aug 25, 2016
mechanisms of cellular stimulation by bacterial endotoxins

Bacterial endotoxins are released into the host organisms when Gram-negative bacteria reproduce or die. The outer membrane of Gram-negative bacteria is formed by two layers organized in an asymmetric manner. The main components of the outer part of these two layers are the lipopolysaccharides (LPS), also known as bacterial endotoxins...


By: Lisa Komski In: Kit LAL
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